IL20 Antibody (PACO20901)
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주문- SKU:
- PACO20901
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | IL20 Antibody (PACO20901) |
Antibody SKU: | PACO20901 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human IL-20 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20901(IL-20 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO20901(IL-20 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. |
Synonyms: | interleukin 20 |
UniProt Protein Function: | IL20: Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3. Belongs to the IL-10 family. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Cytokine; Secreted Chromosomal Location of Human Ortholog: 1q32 Cellular Component: extracellular space; extracellular region Molecular Function:interleukin-20 receptor binding; cytokine activity; interleukin-22 receptor binding Biological Process: positive regulation of osteoclast differentiation; regulation of inflammatory response; positive regulation of epidermal cell differentiation; positive regulation of JAK-STAT cascade; immune response; inflammatory response; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of keratinocyte differentiation |
NCBI Summary: | The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NYY1 |
NCBI GenInfo Identifier: | 38258955 |
NCBI Gene ID: | 50604 |
NCBI Accession: | Q9NYY1.2 |
UniProt Secondary Accession: | Q9NYY1,Q17RB3, Q2THG6, Q96QZ6, |
UniProt Related Accession: | Q9NYY1 |
Molecular Weight: | 176 |
NCBI Full Name: | Interleukin-20 |
NCBI Synonym Full Names: | interleukin 20 |
NCBI Official Symbol: | IL20 |
NCBI Official Synonym Symbols: | IL-20; IL10D; ZCYTO10 |
NCBI Protein Information: | interleukin-20; cytokine Zcyto10; four alpha helix cytokine |
UniProt Protein Name: | Interleukin-20 |
UniProt Synonym Protein Names: | Cytokine Zcyto10 |
Protein Family: | Interleukin |
UniProt Gene Name: | IL20 |
UniProt Entry Name: | IL20_HUMAN |
Antibodies | ELISA Kits |
Anti-IL-20 Antibody (CAB6629) | Human IL-20 CLIA Kit (HUES00207) |
IL20 Antibody (PACO02951) | Human IL-20 ELISA Kit (HUES01514) |
Human IL-20 ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |