IL19 Antibody (PACO19828)
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주문- SKU:
- PACO19828
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | IL19 Antibody (PACO19828) |
Antibody SKU: | PACO19828 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human IL19 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19828(IL19 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Hela cells, mouse liver tissue, Raji cells, Primary antibody: PACO19828(IL19 Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19828(IL19 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-α and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. |
Synonyms: | interleukin 19 |
UniProt Protein Function: | IL19: May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis. Belongs to the IL-10 family. |
UniProt Protein Details: | Protein type:Apoptosis; Secreted; Secreted, signal peptide; Cytokine Chromosomal Location of Human Ortholog: 1q32.2 Cellular Component: extracellular space; extracellular region Molecular Function:cytokine activity Biological Process: apoptosis; positive regulation of JAK-STAT cascade; immune response; inflammatory response; signal transduction; interleukin-6 biosynthetic process |
NCBI Summary: | The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UHD0 |
NCBI GenInfo Identifier: | 146345440 |
NCBI Gene ID: | 29949 |
NCBI Accession: | Q9UHD0.2 |
UniProt Secondary Accession: | Q9UHD0,Q5VUT3, Q96QR4, Q9NUA0, B6VEV9, |
UniProt Related Accession: | Q9UHD0 |
Molecular Weight: | 23,079 Da |
NCBI Full Name: | Interleukin-19 |
NCBI Synonym Full Names: | interleukin 19 |
NCBI Official Symbol: | IL19 |
NCBI Official Synonym Symbols: | MDA1; NG.1; ZMDA1; IL-10C |
NCBI Protein Information: | interleukin-19; melanoma differentiation associated protein-like protein; melanoma differentiation-associated protein-like protein |
UniProt Protein Name: | Interleukin-19 |
UniProt Synonym Protein Names: | Melanoma differentiation-associated protein-like protein; NG.1 |
Protein Family: | Interleukin |
UniProt Gene Name: | IL19 |
UniProt Entry Name: | IL19_HUMAN |
Antibodies | ELISA Kits |
IL19 Antibody (PACO07376) | Human IL-19 ELISA Kit |
Human IL-19 CLIA Kit (HUES00189) | |
Human IL-19 ELISA Kit (HUES01493) | |
Human IL-19 ELISA Kit (HUEB0048) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |