IL18R1 Antibody (PACO14304)
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주문- SKU:
- PACO14304
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | IL18R1 Antibody (PACO14304) |
Antibody SKU: | PACO14304 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human IL18R1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Primary antibody: PACO14304(IL18R1 Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
Background: | The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-α and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. |
Synonyms: | interleukin 18 receptor 1 |
UniProt Protein Function: | IL18R1: Receptor for interleukin 18 (IL-18). Binding to the agonist leads to the activation of NF-kappa-B. Belongs to the interleukin-1 receptor family. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 2q12 Cellular Component: plasma membrane; integral to membrane Molecular Function:protein binding; receptor activity; interleukin-1 receptor activity; interleukin-18 receptor activity Biological Process: positive regulation of interferon-gamma production; T-helper 1 cell differentiation; natural killer cell activation; immune response; positive regulation of NF-kappaB import into nucleus; signal transduction |
NCBI Summary: | The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] |
UniProt Code: | Q13478 |
NCBI GenInfo Identifier: | 26395370 |
NCBI Gene ID: | 8809 |
NCBI Accession: | Q13478.1 |
UniProt Secondary Accession: | Q13478,Q52LC9, B2R9Y5, |
UniProt Related Accession: | Q13478 |
Molecular Weight: | 62,304 Da |
NCBI Full Name: | Interleukin-18 receptor 1 |
NCBI Synonym Full Names: | interleukin 18 receptor 1 |
NCBI Official Symbol: | IL18R1 |
NCBI Official Synonym Symbols: | CD218a; IL18RA; IL1RRP; CDw218a; IL-1Rrp |
NCBI Protein Information: | interleukin-18 receptor 1; IL-18R1; IL1R-rp; IL-18R-1; IL18Ralpha2; cytokine receptor; IL1 receptor-related protein; CD218 antigen-like family member A |
UniProt Protein Name: | Interleukin-18 receptor 1 |
UniProt Synonym Protein Names: | CD218 antigen-like family member A; CDw218a; IL1 receptor-related protein; IL-1Rrp; IL1R-rp; CD_antigen: CD218a |
Protein Family: | Interleukin-18 receptor |
UniProt Gene Name: | IL18R1 |
UniProt Entry Name: | IL18R_HUMAN |