IL10RB Antibody (PACO13966)
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주문- SKU:
- PACO13966
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | IL10RB Antibody (PACO13966) |
Antibody SKU: | PACO13966 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:10000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human IL10RB |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO13966(IL10RB Antibody) at dilution 1/20. (Original magnification: x200). | |
The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO13966(IL10RB Antibody) at dilution 1/20. (Original magnification: x200). |
Background: | The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21. |
Synonyms: | Interleukin-10 receptor subunit beta |
UniProt Protein Function: | Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. |
NCBI Summary: | The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q08334 |
NCBI GenInfo Identifier: | 56757647 |
NCBI Gene ID: | 3588 |
NCBI Accession: | Q08334.2 |
UniProt Secondary Accession: | Q08334,Q9BUU4, |
UniProt Related Accession: | Q08334 |
Molecular Weight: | 36,995 Da |
NCBI Full Name: | Interleukin-10 receptor subunit beta |
NCBI Synonym Full Names: | interleukin 10 receptor subunit beta |
NCBI Official Symbol: | IL10RB |
NCBI Official Synonym Symbols: | CRFB4; CRF2-4; D21S58; D21S66; CDW210B; IL-10R2 |
NCBI Protein Information: | interleukin-10 receptor subunit beta |
UniProt Protein Name: | Interleukin-10 receptor subunit beta |
UniProt Synonym Protein Names: | Cytokine receptor class-II member 4; Cytokine receptor family 2 member 4; CRF2-4; Interleukin-10 receptor subunit 2; IL-10R subunit 2; IL-10R2; CD_antigen: CDw210b |
Protein Family: | Interleukin-10 receptor |
UniProt Gene Name: | IL10RB |
Antibodies | ELISA Kits |
Anti-IL-10RB Antibody (CAB15680) | Human IL-10RB / IL-10 receptor beta ELISA Kit |
IL10RB Antibody (PACO09909) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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