Human Protamine-2/PRM2 Recombinant Protein (RPES3025)

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SKU:
RPES3025
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human Protamine-2/PRM2 Recombinant Protein

Ribonucleoside-Diphosphate Reductase Subunit M2 (RRM2) belongs to the ribonucleoside diphosphate reductase small chain family. The reductase of RRM2 catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. RRM2 supplies the precursors essential for DNA synthesis. RRM2 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Phosphorylation on Ser-20 relieves the inhibitory effect on Wnt signaling.

Product Name:Human Protamine-2/PRM2 Recombinant Protein (RPES3025)
Product Code:RPES3025
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Ribonucleoside-Diphosphate Reductase Subunit M2, Ribonucleotide Reductase Small Chain, Ribonucleotide Reductase Small Subunit, RRM2, RR2
Accession:P31350
Sequence:Met 1-Phe389
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Ribonucleotide Reductase Small Chain is produced by our Mammalian expression system and the target gene encoding Met1-Phe389 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:45.9 kDa
AP Mol Mass:47 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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