Human Kallikrein 11/KLK11 Recombinant Protein (RPES3575)

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SKU:
RPES3575
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human Kallikrein 11/KLK11 Recombinant Protein

Human Kallikrein 11 (KLK11) is a member of tissue kallikrein family which are extracellular serine proteases consisting of 15 members. Two isoforms of KLK11 are differentially expressed. Isoform 1 is predominantly expressed in brain and isoform 2 is preferentially expressed in prostate. Isoform 1 consists of a signal peptide;a short pro peptide and the mature chain.Isoform 2 contains an extra 32 amino acid N terminal to full-length isoform 1.KLK11 is a novel marker for ovarian and prostate cancer carcinomas. KLK11 can be activated by thermolysin and is active against a thioester substrate.

Product Name:Human Kallikrein 11/KLK11 Recombinant Protein (RPES3575)
Product Code:RPES3575
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Kallikrein-11, hK11, Hippostasin, Serine Protease 20, Trypsin-Like Protease, KLK11, PRSS20, TLSP
Accession:NP_006844.1
Sequence:Glu19-Asn250
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Kallikrein 11 is produced by our Mammalian expression system and the target gene encoding Glu19-Asn250 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:26.3 kDa
AP Mol Mass:38 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM TrisHCl; 150mM NaCl; 2mM CaCl2; pH 8.0.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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