HSPA2 Antibody (PACO43960)
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주문- SKU:
- PACO43960
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IP
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | HSPA2 Antibody (PACO43960) |
Antibody SKU: | PACO43960 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IP |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000 |
Species Reactivity: | Human, Rat |
Immunogen: | Recombinant Human Heat shock-related 70 kDa protein 2 protein (400-639AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: HSPA2 antibody at 6µg/ml. Lane 1: A431 whole cell lysate. Lane 2: Hela whole cell lysate. Lane 3: Rat brain tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 70 kDa. Observed band size: 70 kDa. | |
Immunoprecipitating HSPA2 in Hela whole cell lysate. Lane 1: Rabbit control IgG instead of (1µg) instead of PACO43960 in Hela whole cell lysate.For western blotting, a HRP-conjugated anti-rabbit IgG, specific to the non-reduced form of IgG was used as the Secondary antibody (1/50000). Lane 2: PACO43960 (4µg) + Hela whole cell lysate (500µg). Lane 3: Hela whole cell lysate (20µg). | |
Immunohistochemistry of paraffin-embedded human testis tissue using PACO43960 at dilution of 1:100. |
Background: | In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. |
Synonyms: | Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2), HSPA2 |
UniProt Protein Function: | HSPA2: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Interacts with ZNF541. Component of the CatSper complex. Belongs to the heat shock protein 70 family. |
UniProt Protein Details: | Protein type:Heat shock protein; Chaperone Chromosomal Location of Human Ortholog: 14q24.1 Cellular Component: male germ cell nucleus; cell surface; mitochondrion; membrane; synaptonemal complex; nucleus; cytosol Molecular Function:protein binding; enzyme binding; unfolded protein binding; glycolipid binding; ATP binding Biological Process: G2/M-specific positive regulation of cyclin-dependent protein kinase activity; male meiosis I; protein refolding; male meiosis; response to unfolded protein; spermatid development |
UniProt Code: | P54652 |
NCBI GenInfo Identifier: | 1708307 |
NCBI Gene ID: | 3306 |
NCBI Accession: | P54652.1 |
UniProt Secondary Accession: | P54652,Q15508, Q53XM3, Q9UE78, |
UniProt Related Accession: | P54652 |
Molecular Weight: | 70,021 Da |
NCBI Full Name: | Heat shock-related 70 kDa protein 2 |
NCBI Synonym Full Names: | heat shock 70kDa protein 2 |
NCBI Official Symbol: | HSPA2 |
NCBI Official Synonym Symbols: | HSP70-2; HSP70-3 |
NCBI Protein Information: | heat shock-related 70 kDa protein 2; heat shock 70kD protein 2 |
UniProt Protein Name: | Heat shock-related 70 kDa protein 2 |
UniProt Gene Name: | HSPA2 |
UniProt Entry Name: | HSP72_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |