HS6ST1 Antibody (PACO45914)
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주문- SKU:
- PACO45914
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | HS6ST1 Antibody (PACO45914) |
Antibody SKU: | PACO45914 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IF:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Heparan-sulfate 6-O-sulfotransferase 1 protein (3-133AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: HS6ST1 antibody at 2 µg/ml + Mouse skeletal muscle tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 49, 30 kDa. Observed band size: 49 kDa.. | |
Immunofluorescent analysis of HepG2 cells using PACO45914 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Critical for normal neuronal development where it may play a role in neuron branching. May also play a role in limb development. May prefer iduronic acid, |
Synonyms: | Heparan-sulfate 6-O-sulfotransferase 1 (HS6ST-1) (EC 2.8.2.-), HS6ST1, HS6ST |
UniProt Protein Function: | 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Critical for normal neuronal development where it may play a role in neuron branching. May also play a role in limb development. May prefer iduronic acid. |
NCBI Summary: | The protein encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biological activities. This enzyme is a type II integral membrane protein and is responsible for 6-O-sulfation of heparan sulfate. This enzyme does not share significant sequence similarity with other known sulfotransferases. A pseudogene located on chromosome 1 has been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | O60243 |
NCBI GenInfo Identifier: | 148747866 |
NCBI Gene ID: | 9394 |
NCBI Accession: | NP_004798.3 |
UniProt Related Accession: | O60243 |
Molecular Weight: | |
NCBI Full Name: | heparan-sulfate 6-O-sulfotransferase 1 |
NCBI Synonym Full Names: | heparan sulfate 6-O-sulfotransferase 1 |
NCBI Official Symbol: | HS6ST1 |
NCBI Official Synonym Symbols: | HH15; HS6ST |
NCBI Protein Information: | heparan-sulfate 6-O-sulfotransferase 1 |
UniProt Protein Name: | Heparan-sulfate 6-O-sulfotransferase 1 |
Protein Family: | Heparan-sulfate 6-O-sulfotransferase |
UniProt Gene Name: | HS6ST1 |
Antibodies |
Anti-HS6ST1 Antibody (CAB17595) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |