HOMER2 Antibody (PACO16475)
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주문- SKU:
- PACO16475
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | HOMER2 Antibody (PACO16475) |
Antibody SKU: | PACO16475 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human HOMER2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16475(HOMER2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO16475(HOMER2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein is a postsynaptic density scaffolding protein. Alternative splicing results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 14. |
Synonyms: | homer homolog 2 |
UniProt Protein Function: | Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses (PubMed:9808459). Required for normal hearing (PubMed:25816005). |
NCBI Summary: | This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein is a postsynaptic density scaffolding protein. Alternative splicing results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 14. [provided by RefSeq, Jun 2011] |
UniProt Code: | Q9NSB8 |
NCBI GenInfo Identifier: | 46249349 |
NCBI Gene ID: | 9455 |
NCBI Accession: | NP_004830.2 |
UniProt Secondary Accession: | Q9NSB8,O95269, O95349, Q9NSB6, Q9NSB7, Q9UNT7, |
UniProt Related Accession: | Q9NSB8 |
Molecular Weight: | 39,467 Da |
NCBI Full Name: | homer protein homolog 2 isoform 1 |
NCBI Synonym Full Names: | homer scaffold protein 2 |
NCBI Official Symbol: | HOMER2 |
NCBI Official Synonym Symbols: | CPD; ACPD; DFNA68; VESL-2; HOMER-2 |
NCBI Protein Information: | homer protein homolog 2 |
UniProt Protein Name: | Homer protein homolog 2 |
UniProt Synonym Protein Names: | Cupidin |
Protein Family: | Homer protein |
UniProt Gene Name: | HOMER2 |
Antibodies |
Anti-HOMER2 Antibody (CAB16468) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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