HDAC11 Antibody (PACO43743)
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주문- SKU:
- PACO43743
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | HDAC11 Antibody (PACO43743) |
Antibody SKU: | PACO43743 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:200-1:1000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Histone deacetylase 11 protein (1-347AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: HDAC11 antibody at 2µg/ml + Mouse brain tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 40, 34 kDa. Observed band size: 40 kDa. | |
Immunohistochemistry of paraffin-embedded human breast cancer using PACO43743 at dilution of 1:100. |
Background: | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. |
Synonyms: | Histone deacetylase 11 (HD11) (EC 3.5.1.98), HDAC11 |
UniProt Protein Function: | HDAC11: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Belongs to the histone deacetylase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.5.1.98; Deacetylase Chromosomal Location of Human Ortholog: 3p25.1 Cellular Component: histone deacetylase complex; nucleus; plasma membrane Molecular Function:histone deacetylase activity; transcription factor binding Biological Process: chromatin modification; histone deacetylation |
NCBI Summary: | This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2009] |
UniProt Code: | Q96DB2 |
NCBI GenInfo Identifier: | 26394832 |
NCBI Gene ID: | 79885 |
NCBI Accession: | Q96DB2.1 |
UniProt Secondary Accession: | Q96DB2,Q9H6I7, Q9H6X3, Q9NTC9, B4DDK1, |
UniProt Related Accession: | Q96DB2 |
Molecular Weight: | 33,124 Da |
NCBI Full Name: | Histone deacetylase 11 |
NCBI Synonym Full Names: | histone deacetylase 11 |
NCBI Official Symbol: | HDAC11 |
NCBI Official Synonym Symbols: | HD11 |
NCBI Protein Information: | histone deacetylase 11 |
UniProt Protein Name: | Histone deacetylase 11 |
Protein Family: | Histone deacetylase |
UniProt Gene Name: | HDAC11 |
UniProt Entry Name: | HDA11_HUMAN |
Antibodies |
Anti-HDAC11 Antibody (CAB6140) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |