GULP1 Antibody (PACO51130)
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주문- SKU:
- PACO51130
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GULP1 Antibody (PACO51130) |
Antibody SKU: | PACO51130 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IF:1:50-1:200 |
Species Reactivity: | Human, Rat |
Immunogen: | Recombinant Human PTB domain-containing engulfment adapter protein 1 protein (199-279AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: HepG2 whole cell lysate, Rat heart tissue. All lanes: GULP1 antibody at 2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 35, 20, 23, 34 kDa. Observed band size: 45 kDa.. | |
Immunofluorescent analysis of HepG2 cells using PACO51130 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6. |
Synonyms: | PTB domain-containing engulfment adapter protein 1 (Cell death protein 6 homolog) (PTB domain adapter protein CED-6) (Protein GULP), GULP1, CED6 GULP |
UniProt Protein Function: | GULP1: May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6. Belongs to the ced-6 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 2q32.3-q33 Cellular Component: cytoplasm Molecular Function:signal transducer activity Biological Process: apoptosis; phagocytosis, engulfment; lipid transport; signal transduction |
NCBI Summary: | The protein encoded by this gene is an adapter protein necessary for the engulfment of apoptotic cells by phagocytes. Several transcript variants, some protein coding and some thought not to be protein coding, have been found for this gene. [provided by RefSeq, Nov 2011] |
UniProt Code: | Q9UBP9 |
NCBI GenInfo Identifier: | 74720076 |
NCBI Gene ID: | 51454 |
NCBI Accession: | Q9UBP9.1 |
UniProt Secondary Accession: | Q9UBP9,Q53PC1, Q53RF3, Q9BVL3, B2RB51, B4DQ40, B8ZZ72 D3DPH1, E9PB86, |
UniProt Related Accession: | Q9UBP9 |
Molecular Weight: | 304 |
NCBI Full Name: | PTB domain-containing engulfment adapter protein 1 |
NCBI Synonym Full Names: | GULP, engulfment adaptor PTB domain containing 1 |
NCBI Official Symbol: | GULP1 |
NCBI Official Synonym Symbols: | CED6; GULP; CED-6 |
NCBI Protein Information: | PTB domain-containing engulfment adapter protein 1; cell death protein 6 homolog; PTB domain adapter protein CED-6; PTB domain adaptor protein CED-6 |
UniProt Protein Name: | PTB domain-containing engulfment adapter protein 1 |
UniProt Synonym Protein Names: | Cell death protein 6 homolog; PTB domain adapter protein CED-6; Protein GULP |
Protein Family: | PTB domain-containing engulfment adapter protein |
UniProt Gene Name: | GULP1 |
UniProt Entry Name: | GULP1_HUMAN |
Antibodies | ELISA Kits |
Anti-GULP1 Antibody (CAB3432) | Human GULP1 (PTB domain-containing engulfment adapter protein 1) ELISA Kit (HUFI04000) |
GULP1 Antibody (PACO09649) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |