GRB2 Antibody (PACO14477)
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주문- SKU:
- PACO14477
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GRB2 Antibody (PACO14477) |
Antibody SKU: | PACO14477 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:10-1:50 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Full length fusion protein |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO14477(GRB2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO14477(GRB2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Synonyms: | growth factor receptor-bound protein 2 |
UniProt Protein Function: | Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. |
NCBI Summary: | The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | P62993 |
NCBI GenInfo Identifier: | 51702266 |
NCBI Gene ID: | 2885 |
NCBI Accession: | P62993.1 |
UniProt Secondary Accession: | P62993,P29354, Q14450, Q63057, Q63059, |
UniProt Related Accession: | P62993 |
Molecular Weight: | 20,557 Da |
NCBI Full Name: | Growth factor receptor-bound protein 2 |
NCBI Synonym Full Names: | growth factor receptor bound protein 2 |
NCBI Official Symbol: | GRB2 |
NCBI Official Synonym Symbols: | ASH; Grb3-3; MST084; NCKAP2; MSTP084; EGFRBP-GRB2 |
NCBI Protein Information: | growth factor receptor-bound protein 2 |
UniProt Protein Name: | Growth factor receptor-bound protein 2 |
UniProt Synonym Protein Names: | Adapter protein GRB2; Protein Ash; SH2/SH3 adapter GRB2 |
Protein Family: | Growth factor receptor-bound protein |
UniProt Gene Name: | GRB2 |
UniProt Entry Name: | GRB2_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |