GNB1 Antibody (PACO14438)
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주문- SKU:
- PACO14438
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GNB1 Antibody (PACO14438) |
Antibody SKU: | PACO14438 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human GNB1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO14438(GNB1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 15%SDS-PAGE, Lysate: 40 μg, Lane 1-4: HepG2 cells, A549 cells, 293T cells, 231 cells, Primary antibody: PACO14438(GNB1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second. | |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO14438(GNB1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a γ subunit. These subunits are encoded by families of related genes. This gene encodes a β subunit. β subunits are important regulators of α subunits, as well as of certain signal transduction receptors and effectors. This gene uses alternative polyadenylation signals. |
Synonyms: | guanine nucleotide binding protein (G protein), β polypeptide 1 |
UniProt Protein Function: | G-beta 1: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the WD repeat G protein beta family. |
UniProt Protein Details: | Protein type:G protein, heterotrimeric beta; G protein, heterotrimeric; G protein Chromosomal Location of Human Ortholog: 1p36.33 Cellular Component: cytosol; heterotrimeric G-protein complex; intracellular; lysosomal membrane; membrane; plasma membrane Molecular Function:GTPase activity; GTPase binding; protein binding; protein complex binding Biological Process: acetylcholine receptor signaling, muscarinic pathway; dopamine receptor, adenylate cyclase activating pathway; platelet activation; protein folding; Ras protein signal transduction; rhodopsin mediated signaling; signal transduction; Wnt receptor signaling pathway, calcium modulating pathway |
NCBI Summary: | Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
UniProt Code: | P62873 |
NCBI GenInfo Identifier: | 51317302 |
NCBI Gene ID: | 2782 |
NCBI Accession: | P62873.3 |
UniProt Secondary Accession: | P62873,P04697, P04901, Q1RMY8, B1AJZ7, |
UniProt Related Accession: | P62873 |
Molecular Weight: | 36,298 Da |
NCBI Full Name: | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 |
NCBI Synonym Full Names: | G protein subunit beta 1 |
NCBI Official Symbol: | GNB1 |
NCBI Official Synonym Symbols: | MRD42 |
NCBI Protein Information: | guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 |
UniProt Protein Name: | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 |
UniProt Synonym Protein Names: | Transducin beta chain 1 |
UniProt Gene Name: | GNB1 |
UniProt Entry Name: | GBB1_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |