GLYR1 Antibody (PACO19720)
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주문- SKU:
- PACO19720
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GLYR1 Antibody (PACO19720) |
Antibody SKU: | PACO19720 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human GLYR1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Hela cells, Jurkat cells, K562 cells, HUVEC cells, Primary antibody: PACO19720(GLYR1 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds. |
Background: | Glyoxylate reductase 1 homolog (Arabidopsis) encodes a deduced 553-amino acid, protein with a molecular mass of 60.5 kDa. GLYR1 contains 2 nuclear localization signals, an N-terminal PWWP domain and an AT-hook, and a C-terminal NAD-binding domain. Western blot, RT-PCR, and immunohistochemistry showed that GLYR1 localizes to the nucleus in a variety of cell lines. |
Synonyms: | glyoxylate reductase 1 homolog (Arabidopsis) |
UniProt Protein Function: | Putative oxidoreductase that is recruited on chromatin and promotes KDM1B demethylase activity (PubMed:23260659). Recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3) (PubMed:20850016). Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling (PubMed:16352664). Indirectly promotes phosphorylation of MAPK14 and activation of ATF2 (PubMed:16352664). The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6 (PubMed:16352664). |
UniProt Code: | Q49A26 |
NCBI GenInfo Identifier: | 862669336 |
NCBI Gene ID: | 84656 |
NCBI Accession: | NP_001295025.1 |
UniProt Secondary Accession: | Q49A26,Q5U632, Q6P1Q2, Q6V3W7, Q9BTI1, Q9BXK2, B4DL47 C9JJ40, C9JJ60, |
UniProt Related Accession: | Q49A26 |
Molecular Weight: | 52,559 Da |
NCBI Full Name: | putative oxidoreductase GLYR1 isoform 2 |
NCBI Synonym Full Names: | glyoxylate reductase 1 homolog |
NCBI Official Symbol: | GLYR1 |
NCBI Official Synonym Symbols: | NP60; BM045; HIBDL; N-PAC |
NCBI Protein Information: | putative oxidoreductase GLYR1 |
UniProt Protein Name: | Putative oxidoreductase GLYR1 |
UniProt Synonym Protein Names: | 3-hydroxyisobutyrate dehydrogenase-like protein; Cytokine-like nuclear factor N-PAC; Glyoxylate reductase 1 homolog; Nuclear protein NP60; Nuclear protein of 60 kDa |
UniProt Gene Name: | GLYR1 |
Antibodies | ELISA Kits |
Anti-GLYR1 Antibody (CAB9046) | Human GLYR1 (Glyoxylate reductase 1 homolog) ELISA Kit (HUFI04102) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |