GLIPR1 Antibody (PACO16417)
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주문- SKU:
- PACO16417
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GLIPR1 Antibody (PACO16417) |
Antibody SKU: | PACO16417 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:100-1:300 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human GLIPR1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO16417(GLIPR1 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse kidney tissue, Primary antibody: PACO16417(GLIPR1 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16417(GLIPR1 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. |
Synonyms: | GLI pathogenesis-related 1 |
UniProt Protein Function: | GLIPR1: a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 12q21.2 Cellular Component: membrane; plasma membrane Biological Process: neutrophil degranulation; regulation of lipid metabolic process |
NCBI Summary: | This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] |
UniProt Code: | P48060 |
NCBI GenInfo Identifier: | 110825980 |
NCBI Gene ID: | 11010 |
NCBI Accession: | NP_006842.2 |
UniProt Secondary Accession: | P48060,Q15409, Q969K2, A7YET6, F8VUC2, |
UniProt Related Accession: | P48060 |
Molecular Weight: | 28.2kD |
NCBI Full Name: | glioma pathogenesis-related protein 1 |
NCBI Synonym Full Names: | GLI pathogenesis related 1 |
NCBI Official Symbol: | GLIPR1 |
NCBI Official Synonym Symbols: | GLIPR; RTVP1; CRISP7 |
NCBI Protein Information: | glioma pathogenesis-related protein 1 |
UniProt Protein Name: | Glioma pathogenesis-related protein 1 |
UniProt Synonym Protein Names: | Protein RTVP-1 |
Protein Family: | GDSL esterase/lipase |
UniProt Gene Name: | GLIPR1 |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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