GJA4 Antibody (PACO26985)
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주문- SKU:
- PACO26985
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GJA4 Antibody (PACO26985) |
Antibody SKU: | PACO26985 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Gap junction alpha-4 protein (231-333AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO26985 at dilution of 1:100. | |
Immunofluorescent analysis of Hela cells using PACO26985 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). | |
Immunohistochemistry of paraffin-embedded human heart tissue using PACO26985 at dilution of 1:100. |
Background: | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. |
Synonyms: | Gap junction alpha-4 protein (Connexin-37) (Cx37), GJA4 |
UniProt Protein Function: | GJA4: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Alpha-type (group II) subfamily. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Cell adhesion; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 1p35.1 Cellular Component: connexon complex; integral to plasma membrane; gap junction Molecular Function:protein binding Biological Process: intercellular junction assembly; blood vessel development; cell-cell signaling; transport; calcium ion transport; response to pain |
NCBI Summary: | This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction. [provided by RefSeq, Jul 2008] |
UniProt Code: | P35212 |
NCBI GenInfo Identifier: | 8928555 |
NCBI Gene ID: | 2701 |
NCBI Accession: | P35212.3 |
UniProt Secondary Accession: | P35212,Q9P106, Q9UBL1, Q9UNA9, Q9UNB0, Q9UNB1, Q9Y5N7 A8K698, D3DPR4, |
UniProt Related Accession: | P35212 |
Molecular Weight: | |
NCBI Full Name: | Gap junction alpha-4 protein |
NCBI Synonym Full Names: | gap junction protein, alpha 4, 37kDa |
NCBI Official Symbol: | GJA4 |
NCBI Official Synonym Symbols: | CX37 |
NCBI Protein Information: | gap junction alpha-4 protein; connexin 37; connexin-37 |
UniProt Protein Name: | Gap junction alpha-4 protein |
UniProt Synonym Protein Names: | Connexin-37; Cx37 |
Protein Family: | Gap junction alpha-4 protein |
UniProt Gene Name: | GJA4 |
UniProt Entry Name: | CXA4_HUMAN |