GGCT Antibody (PACO13688)
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주문- SKU:
- PACO13688
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GGCT Antibody (PACO13688) |
Antibody SKU: | PACO13688 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human GGCT |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | gamma-glutamyl cyclotransferase;GGCT;C7orf24;CRF21;FLJ11717;GCTG;Ggc;MGC3077 ; |
UniProt Protein Function: | GGCT: Catalyzes the formation of 5-oxoproline from gamma- glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis. Belongs to the gamma-glutamylcyclotransferase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 2.3.2.4; Transferase; Apoptosis; Other Amino Acids Metabolism - glutathione Chromosomal Location of Human Ortholog: 7p15-p14 Cellular Component: cytosol Molecular Function:gamma-glutamylcyclotransferase activity; protein homodimerization activity Biological Process: glutathione biosynthetic process; release of cytochrome c from mitochondria |
NCBI Summary: | The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] |
UniProt Code: | O75223 |
NCBI GenInfo Identifier: | 34222503 |
NCBI Gene ID: | 79017 |
NCBI Accession: | O75223.1 |
UniProt Secondary Accession: | O75223,Q9BS37, B2RDN0, B8ZZN4, B8ZZR8, |
UniProt Related Accession: | O75223 |
Molecular Weight: | 19,092 Da |
NCBI Full Name: | Gamma-glutamylcyclotransferase |
NCBI Synonym Full Names: | gamma-glutamylcyclotransferase |
NCBI Official Symbol: | GGCT |
NCBI Official Synonym Symbols: | GGC; GCTG; CRF21; C7orf24 |
NCBI Protein Information: | gamma-glutamylcyclotransferase |
UniProt Protein Name: | Gamma-glutamylcyclotransferase |
UniProt Synonym Protein Names: | Cytochrome c-releasing factor 21 |
Protein Family: | Gamma-glutamylcyclotransferase |
UniProt Gene Name: | GGCT |
UniProt Entry Name: | GGCT_HUMAN |