GCGR Antibody (PACO19714)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO19714
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GCGR Antibody (PACO19714) |
Antibody SKU: | PACO19714 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human GCGR |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19714(GCGR Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM). |
Synonyms: | glucagon receptor |
UniProt Protein Function: | GCGR: This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 2 family. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; GPCR, family 2; Membrane protein, integral; Receptor, GPCR Chromosomal Location of Human Ortholog: 17q25 Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane Molecular Function:glucagon receptor activity; guanyl-nucleotide exchange factor activity Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; generation of precursor metabolites and energy; glucose homeostasis; regulation of blood pressure; response to nutrient; response to starvation Disease: Diabetes Mellitus, Noninsulin-dependent |
NCBI Summary: | The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[provided by RefSeq, Jan 2010] |
UniProt Code: | P47871 |
NCBI GenInfo Identifier: | 1346144 |
NCBI Gene ID: | 2642 |
NCBI Accession: | P47871.1 |
UniProt Secondary Accession: | P47871,Q2M3M5, |
UniProt Related Accession: | P47871 |
Molecular Weight: | 54,009 Da |
NCBI Full Name: | Glucagon receptor |
NCBI Synonym Full Names: | glucagon receptor |
NCBI Official Symbol: | GCGR |
NCBI Official Synonym Symbols: | GGR; GL-R |
NCBI Protein Information: | glucagon receptor |
UniProt Protein Name: | Glucagon receptor |
Protein Family: | Glucagon receptor |
UniProt Gene Name: | GCGR |
UniProt Entry Name: | GLR_HUMAN |