FGD5 Antibody (PACO44763)
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주문- SKU:
- PACO44763
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | FGD5 Antibody (PACO44763) |
Antibody SKU: | PACO44763 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human FYVE, RhoGEF and PH domain-containing protein 5 protein (1203-1462AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human gastric cancer using PACO44763 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human bladder cancer using PACO44763 at dilution of 1:100. |
Background: | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape. |
Synonyms: | FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23), FGD5, ZFYVE23 |
UniProt Protein Function: | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape. |
UniProt Code: | Q6ZNL6 |
NCBI GenInfo Identifier: | 23271578 |
NCBI Gene ID: | 152273 |
NCBI Accession: | BC035364 |
UniProt Secondary Accession: | Q6ZNL6,Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4, B3KVQ3 |
UniProt Related Accession: | Q6ZNL6 |
Molecular Weight: | 61,238 Da |
NCBI Full Name: | Homo sapiens FYVE, RhoGEF and PH domain containing 5, mRNA |
NCBI Synonym Full Names: | FYVE, RhoGEF and PH domain containing 5 |
NCBI Official Symbol: | FGD5 |
NCBI Official Synonym Symbols: | ZFYVE23 |
NCBI Protein Information: | FYVE, RhoGEF and PH domain-containing protein 5 |
UniProt Protein Name: | FYVE, RhoGEF and PH domain-containing protein 5 |
UniProt Synonym Protein Names: | Zinc finger FYVE domain-containing protein 23 |
Protein Family: | FYVE, RhoGEF and PH domain-containing protein |
UniProt Gene Name: | FGD5 |