FDFT1 Antibody (PACO43235)
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주문- SKU:
- PACO43235
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | FDFT1 Antibody (PACO43235) |
Antibody SKU: | PACO43235 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Squalene synthase protein (1-260AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: FDFT1 antibody at 2µg/ml. Lane 1: 293T whole cell lysate. Lane 2: Mouse liver tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 49, 41, 39, 36, 44 kDa. Observed band size: 49 kDa. | |
Immunohistochemistry of paraffin-embedded human lung cancer using PACO43235 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human liver cancer using PACO43235 at dilution of 1:100. |
Synonyms: | Squalene synthase (SQS) (SS) (EC 2.5.1.21) (FPP:FPP farnesyltransferase) (Farnesyl-diphosphate farnesyltransferase), FDFT1 |
UniProt Protein Function: | FDFT1: a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008] |
UniProt Protein Details: | Protein type:Oxidoreductase; EC 2.5.1.21; Endoplasmic reticulum; Lipid Metabolism - steroid biosynthesis; Membrane protein, integral; Transferase; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 8p23.1-p22 Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane Molecular Function:farnesyl-diphosphate farnesyltransferase activity Biological Process: cholesterol biosynthetic process; steroid biosynthetic process |
NCBI Summary: | This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008] |
UniProt Code: | P37268 |
NCBI GenInfo Identifier: | 585126 |
NCBI Gene ID: | 2222 |
NCBI Accession: | P37268.1 |
UniProt Secondary Accession: | P37268,Q96GT0, B3KQ95, B4DJE5, B4DT56, B7Z1J3, |
UniProt Related Accession: | P37268 |
Molecular Weight: | 43,060 Da |
NCBI Full Name: | Squalene synthase |
NCBI Synonym Full Names: | farnesyl-diphosphate farnesyltransferase 1 |
NCBI Official Symbol: | FDFT1 |
NCBI Official Synonym Symbols: | SS; SQS; DGPT; ERG9 |
NCBI Protein Information: | squalene synthase |
UniProt Protein Name: | Squalene synthase |
UniProt Synonym Protein Names: | FPP:FPP farnesyltransferase; Farnesyl-diphosphate farnesyltransferase |
UniProt Gene Name: | FDFT1 |
UniProt Entry Name: | FDFT_HUMAN |
Antibodies | ELISA Kits |
Anti-SQS/FDFT1 Antibody (CAB6229) | Human Squalene synthase (FDFT1) ELISA Kit |
Anti-SQS/FDFT1 Antibody (CAB4651) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |