ERCC4 Antibody (PACO21670)
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주문- SKU:
- PACO21670
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ERCC4 Antibody (PACO21670) |
Antibody SKU: | PACO21670 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthesized peptide derived from internal of human XPF. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from 293 cells, using XPF antibody. |
Background: | Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. Involved in homologous recombination that assists in removing interstrand cross-link. Sijbers A.M., Cell 86:811-822(1996). |
Synonyms: | DNA repair endonuclease XPF; EC 3.1; DNA excision repair protein ERCC-4; DNA-repair protein complementing XP-F cells; Xeroderma pigmentosum group F-complementing protein |
UniProt Protein Function: | Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. Involved in homologous recombination that assists in removing interstrand cross-link. |
NCBI Summary: | The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).[provided by RefSeq, Mar 2009] |
UniProt Code: | Q92889 |
NCBI GenInfo Identifier: | 4885217 |
NCBI Gene ID: | 2072 |
NCBI Accession: | NP_005227.1 |
UniProt Secondary Accession: | Q92889,O00140, Q8TD83, A5PKV6, A8K111, |
UniProt Related Accession: | Q92889 |
Molecular Weight: | 103 kDa |
NCBI Full Name: | DNA repair endonuclease XPF |
NCBI Synonym Full Names: | ERCC excision repair 4, endonuclease catalytic subunit |
NCBI Official Symbol: | ERCC4 |
NCBI Official Synonym Symbols: | XPF; RAD1; FANCQ; XFEPS; ERCC11 |
NCBI Protein Information: | DNA repair endonuclease XPF |
UniProt Protein Name: | DNA repair endonuclease XPF |
UniProt Synonym Protein Names: | DNA excision repair protein ERCC-4; DNA repair protein complementing XP-F cells; Xeroderma pigmentosum group F-complementing protein |
Protein Family: | Positive control factor |
UniProt Gene Name: | ERCC4 |
Antibodies | ELISA Kits |
Anti-ERCC4 Antibody (CAB8119) | XPF Colorimetric Cell-Based ELISA Kit |
ERCC4 Antibody (PACO06472) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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