ERBB4 Antibody (PACO14241)
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주문- SKU:
- PACO14241
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ERBB4 Antibody (PACO14241) |
Antibody SKU: | PACO14241 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human ERBB4 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO14241(ERBB4 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Hela cells, Primary antibody: PACO14241(ERBB4 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO14241(ERBB4 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. |
Synonyms: | erb-b2 receptor tyrosine kinase 4 |
NCBI Summary: | This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q15303 |
NCBI GenInfo Identifier: | 3913590 |
NCBI Gene ID: | 2066 |
NCBI Accession: | |
UniProt Related Accession: | Q15303 |
Molecular Weight: | |
NCBI Full Name: | Receptor tyrosine-protein kinase erbB-4 |
NCBI Synonym Full Names: | erb-b2 receptor tyrosine kinase 4 |
NCBI Official Symbol: | ERBB4 |
NCBI Official Synonym Symbols: | HER4; ALS19; p180erbB4 |
NCBI Protein Information: | receptor tyrosine-protein kinase erbB-4 |
UniProt Protein Name: | |
UniProt Gene Name: |
Antibodies |
Anti-ERBB4 Antibody (CAB0749) |
Anti-ERBB4 Antibody (CAB6133) |
Anti-Phospho-ERBB4-Y1284 Antibody (CABP0034) |
Anti-ErbB4 Antibody (CAB19047) |
Phospho-ERBB4 (Y1284) Antibody (PACO03632) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |