EPCAM Antibody (PACO21734)
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주문- SKU:
- PACO21734
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | EPCAM Antibody (PACO21734) |
Antibody SKU: | PACO21734 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human TACD1. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Perez M.S., J. Immunol. 142:3662-3667(1989). |
Clonality: | Polyclonal |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from Jurkat cells, HuvEc cells and COLO205 cells, using TACD1 antibody. |
Synonyms: | Tumor-associated calcium signal transducer 1 [Precursor]; Major gastrointestinal tumor-associated protein GA733-2; Epithelial cell surface antigen; Epithelial glycoprotein; EGP |
UniProt Protein Function: | EPCAM: a single-pass type I membrane protein of the EPCAM family. May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinomas including pancreatic carcinoma. May be a marker of cancer stem cells. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Motility/polarity/chemotaxis Cellular Component: tight junction; cell surface; membrane; basolateral plasma membrane; apical plasma membrane; plasma membrane; integral to membrane; cell junction; lateral plasma membrane Molecular Function:protein complex binding Biological Process: positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; stem cell differentiation; negative regulation of apoptosis |
UniProt Code: | P16422 |
NCBI GenInfo Identifier: | 112293275 |
NCBI Gene ID: | 17075 |
NCBI Accession: | NP_032558.2 |
UniProt Secondary Accession: | P16422,Q61512, |
UniProt Related Accession: | Q99JW5 |
Molecular Weight: | |
NCBI Full Name: | epithelial cell adhesion molecule |
NCBI Synonym Full Names: | epithelial cell adhesion molecule |
NCBI Official Symbol: | Epcam |
NCBI Official Synonym Symbols: | EGP; Ly74; gp40; CD326; EGP-2; TROP1; Egp314; Ep-CAM; EpCAM1; Tacsd1; GA733-2; Tacstd1 |
NCBI Protein Information: | epithelial cell adhesion molecule |
UniProt Protein Name: | Epithelial cell adhesion molecule |
UniProt Synonym Protein Names: | Epithelial glycoprotein 314; EGP314; mEGP314; Protein 289A; Tumor-associated calcium signal transducer 1; CD_antigen: CD326 |
Protein Family: | Epithelial cell adhesion molecule |
UniProt Gene Name: | Epcam |
UniProt Entry Name: | EPCAM_MOUSE |
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