UniProt Protein Function: | In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. |
NCBI Summary: | The protein encoded by this gene is a plasma membrane protein that hydrolyzes extracellular ATP and ADP to AMP. Inhibition of this protein's activity may confer anticancer benefits. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015] |
UniProt Code: | P49961 |
NCBI GenInfo Identifier: | 1705710 |
NCBI Gene ID: | 953 |
NCBI Accession: | P49961.1 |
UniProt Secondary Accession: | P49961,Q5T561, Q5T562, Q86VV3, Q9UQQ9, Q9Y3Q9, A9Z1X8 B4DWB9, B4E1X1, B7Z599, G3XAF6, |
UniProt Related Accession: | P49961 |
Molecular Weight: | 59,325 Da |
NCBI Full Name: | Ectonucleoside triphosphate diphosphohydrolase 1 |
NCBI Synonym Full Names: | ectonucleoside triphosphate diphosphohydrolase 1 |
NCBI Official Symbol: | ENTPD1 |
NCBI Official Synonym Symbols: | CD39; SPG64; ATPDase; NTPDase-1 |
NCBI Protein Information: | ectonucleoside triphosphate diphosphohydrolase 1 |
UniProt Protein Name: | Ectonucleoside triphosphate diphosphohydrolase 1 |
UniProt Synonym Protein Names: | Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen; CD_antigen: CD39 |
UniProt Gene Name: | ENTPD1 |
UniProt Entry Name: | ENTP1_HUMAN |