EIF4EBP2 Antibody (PACO15885)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO15885
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | EIF4EBP2 Antibody (PACO15885) |
Antibody SKU: | PACO15885 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human EIF4EBP2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15885(EIF4EBP2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15885(EIF4EBP2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. |
Synonyms: | eukaryotic translation initiation factor 4E binding protein 2 |
UniProt Protein Function: | 4E-BP2: eukaryotic translation initiation factor 4E binding protein 2 |
UniProt Protein Details: | Protein type:Translation; Translation initiation Chromosomal Location of Human Ortholog: 10q21-q22 Cellular Component: cytoplasm Molecular Function:eukaryotic initiation factor 4E binding; protein binding; translation repressor activity Biological Process: cAMP-mediated signaling; insulin receptor signaling pathway; memory; negative regulation of translational initiation; regulation of synaptic plasticity; regulation of synaptic transmission; social behavior; TOR signaling pathway; translation |
NCBI Summary: | This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008] |
UniProt Code: | Q13542 |
NCBI GenInfo Identifier: | 34921510 |
NCBI Gene ID: | 1979 |
NCBI Accession: | Q13542.1 |
UniProt Related Accession: | Q13542 |
Molecular Weight: | 12,939 Da |
NCBI Full Name: | Eukaryotic translation initiation factor 4E-binding protein 2 |
NCBI Synonym Full Names: | eukaryotic translation initiation factor 4E binding protein 2 |
NCBI Official Symbol: | EIF4EBP2 |
NCBI Official Synonym Symbols: | 4EBP2; PHASII |
NCBI Protein Information: | eukaryotic translation initiation factor 4E-binding protein 2 |
UniProt Protein Name: | Eukaryotic translation initiation factor 4E-binding protein 2 |
UniProt Gene Name: | EIF4EBP2 |
UniProt Entry Name: | 4EBP2_HUMAN |