EIF3L Antibody (PACO00748)
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주문- SKU:
- PACO00748
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | EIF3L Antibody |
Antibody SKU: | PACO00748 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IF |
Recommended Dilutions: | WB:1:500-1:2000, IF:1:200-1:1000 |
Species Reactivity: | Human, Mouse |
Immunogen: | synthesized peptide derived from the N-terminal region of human eIF3L. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | EIF3L; EIF3EIP; EIF3S6IP; HSPC021; HSPC025; MSTP005; Eukaryotic translation initiation factor 3 subunit L; eIF3l; Eukaryotic translation initiation factor 3 subunit 6-interacting protein; Eukaryotic translation initiation factor 3 subunit E |
UniProt Protein Function: | eIF3S6IP: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Belongs to the eIF-3 subunit L family. |
UniProt Protein Details: | Protein type:RNA-binding; Translation; Translation initiation Chromosomal Location of Human Ortholog: 22q Cellular Component: cytosol; eukaryotic translation initiation factor 3 complex; fibrillar center; membrane; nucleoplasm Molecular Function:protein binding; translation initiation factor activity Biological Process: cellular protein metabolic process; formation of translation preinitiation complex; gene expression; regulation of translational initiation; translation; translational initiation |
UniProt Code: | Q9Y262 |
NCBI GenInfo Identifier: | 339275831 |
NCBI Gene ID: | 51386 |
NCBI Accession: | NP_001229852.1 |
UniProt Secondary Accession: | Q9Y262,Q53HQ1, Q53HT4, Q5QTR1, Q5TI15, Q6ICD2, B2RDG6 B4DYB2, G8JLH4, |
UniProt Related Accession: | Q9Y262 |
Molecular Weight: | Calculated MW: 61kDa/66kDaObserved MW: 67kDa |
NCBI Full Name: | eukaryotic translation initiation factor 3 subunit L isoform 2 |
NCBI Synonym Full Names: | eukaryotic translation initiation factor 3 subunit L |
NCBI Official Symbol: | EIF3L |
NCBI Official Synonym Symbols: | EIF3EIP; EIF3S11; HSPC021; HSPC025; MSTP005; EIF3S6IP |
NCBI Protein Information: | eukaryotic translation initiation factor 3 subunit L |
UniProt Protein Name: | Eukaryotic translation initiation factor 3 subunit L |
UniProt Synonym Protein Names: | Eukaryotic translation initiation factor 3 subunit 6-interacting protein |
UniProt Gene Name: | EIF3L |
UniProt Entry Name: | EIF3L_HUMAN |