EGR4 Antibody (PACO17823)
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주문- SKU:
- PACO17823
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | EGR4 Antibody (PACO17823) |
Antibody SKU: | PACO17823 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human EGR4 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO17823(EGR4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 6%SDS-PAGE,Lysate: 40 μg,,Primary antibody: PACO17823(EGR4 Antibody) at dilution 1/300 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 30 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO17823(EGR4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | Early growth response protein 4 (EGR-4), also known as AT133, is a protein that in humans is encoded by the EGR4 gene. EGR-4 is a member of the early growth response (EGF) family of zinc finger transcription factors. Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCGGGGGCG-3' (GSG). Activates the transcription of target genes whose products are required for mitogenesis and differentiation. |
Synonyms: | early growth response 4 |
UniProt Protein Function: | EGR4: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCGGGGGCG-3' (GSG). Activates the transcription of target genes whose products are required for mitogenesis and differentiation. Belongs to the EGR C2H2-type zinc-finger protein family. |
UniProt Protein Details: | Protein type:C2H2-type zinc finger protein; DNA-binding Chromosomal Location of Human Ortholog: 2p13 Cellular Component: cytoplasm; nucleus Molecular Function:DNA binding; metal ion binding; transcription factor activity Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; positive regulation of cell proliferation; negative regulation of apoptosis |
UniProt Code: | Q05215 |
NCBI GenInfo Identifier: | 485956294 |
NCBI Gene ID: | 1961 |
NCBI Accession: | Q05215.3 |
UniProt Secondary Accession: | Q05215,Q2Z1P5, B2RAE3, G3V1T5, |
UniProt Related Accession: | Q05215 |
Molecular Weight: | 589 |
NCBI Full Name: | Early growth response protein 4 |
NCBI Synonym Full Names: | early growth response 4 |
NCBI Official Symbol: | EGR4 |
NCBI Official Synonym Symbols: | NGFIC; NGFI-C; PAT133 |
NCBI Protein Information: | early growth response protein 4; AT133; EGR-4 |
UniProt Protein Name: | Early growth response protein 4 |
UniProt Synonym Protein Names: | AT133 |
Protein Family: | Early growth response protein |
UniProt Gene Name: | EGR4 |
UniProt Entry Name: | EGR4_HUMAN |