ECSIT Antibody (PACO43729)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO43729
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ECSIT Antibody (PACO43729) |
Antibody SKU: | PACO43729 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial protein (185-431AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial antibody at 10µg/ml + Jurkat whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 50, 34, 25 kDa. Observed band size: 50 kDa. | |
Immunohistochemistry of paraffin-embedded human testis tissue using PACO43729 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO43729 at dilution of 1:100. |
Background: | Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity). Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase. |
Synonyms: | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (Protein SITPEC), ECSIT |
UniProt Protein Function: | ECSIT: Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development. Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase. Belongs to the ECSIT family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transcription factor; Adaptor/scaffold Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: cytoplasm; mitochondrial inner membrane; mitochondrion; nucleoplasm; nucleus Molecular Function:oxidoreductase activity, acting on NADH or NADPH; protein binding Biological Process: mitochondrial respiratory chain complex I assembly; regulation of oxidoreductase activity |
UniProt Code: | Q9BQ95 |
NCBI GenInfo Identifier: | 74752234 |
NCBI Gene ID: | 51295 |
NCBI Accession: | Q9BQ95.1 |
UniProt Secondary Accession: | Q9BQ95,Q96HQ7, Q9NYI1, E9PAN9, K7EMM0, |
UniProt Related Accession: | Q9BQ95 |
Molecular Weight: | 33,938 Da |
NCBI Full Name: | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial |
NCBI Synonym Full Names: | ECSIT signalling integrator |
NCBI Official Symbol: | ECSIT |
NCBI Official Synonym Symbols: | SITPEC |
NCBI Protein Information: | evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial |
UniProt Protein Name: | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial |
UniProt Synonym Protein Names: | Protein SITPEC |
Protein Family: | Evolutionarily conserved signaling intermediate |
UniProt Gene Name: | ECSIT |
UniProt Entry Name: | ECSIT_HUMAN |