EAF2 Antibody (PACO45498)
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주문- SKU:
- PACO45498
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | EAF2 Antibody (PACO45498) |
Antibody SKU: | PACO45498 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human ELL-associated factor 2 protein (1-170AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human brain tissue using PACO45498 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human heart tissue using PACO45498 at dilution of 1:100. |
Background: | Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity). Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo. |
Synonyms: | ELL-associated factor 2 (Testosterone-regulated apoptosis inducer and tumor suppressor protein), EAF2, TRAITS |
UniProt Protein Function: | EAF2: Acts as a transcriptional transactivator of TCEA1 elongation activity. Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo. Belongs to the EAF family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 3q13.33 Cellular Component: transcription elongation factor complex; nuclear speck Molecular Function:protein binding Biological Process: transcription, DNA-dependent; apoptosis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of cell growth |
UniProt Code: | Q96CJ1 |
NCBI GenInfo Identifier: | 73919269 |
NCBI Gene ID: | 55840 |
NCBI Accession: | Q96CJ1.1 |
UniProt Related Accession: | Q96CJ1 |
Molecular Weight: | 35kDa |
NCBI Full Name: | ELL-associated factor 2 |
NCBI Synonym Full Names: | ELL associated factor 2 |
NCBI Official Symbol: | EAF2 |
NCBI Official Synonym Symbols: | U19; BM040; TRAITS |
NCBI Protein Information: | ELL-associated factor 2 |
UniProt Protein Name: | ELL-associated factor 2 |
UniProt Synonym Protein Names: | Testosterone-regulated apoptosis inducer and tumor suppressor protein |
Protein Family: | ELL-associated factor |
UniProt Gene Name: | EAF2 |
UniProt Entry Name: | EAF2_HUMAN |