DSG3 Antibody (PACO52946)
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주문- SKU:
- PACO52946
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | DSG3 Antibody (PACO52946) |
Antibody SKU: | PACO52946 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Desmoglein-3 protein (50-615AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Mouse brain tissue. All lanes: DSG3 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. predicted band size: 108 kDa. observed band size: 108 kDa. |
Background: | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
Synonyms: | Desmoglein-3 (130 kDa pemphigus vulgaris antigen) (PVA) (Cadherin family member 6), DSG3, CDHF6 |
UniProt Protein Function: | DSG3: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Cell adhesion Chromosomal Location of Human Ortholog: 18q12.1 Cellular Component: desmosome; plasma membrane; integral to membrane; cytosol Molecular Function:calcium ion binding Biological Process: apoptosis; homophilic cell adhesion; cell structure disassembly during apoptosis |
NCBI Summary: | Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. [provided by RefSeq, Jul 2008] |
UniProt Code: | P32926 |
NCBI GenInfo Identifier: | 239938621 |
NCBI Gene ID: | 1830 |
NCBI Accession: | P32926.2 |
UniProt Secondary Accession: | P32926,A8K2V2, |
UniProt Related Accession: | P32926 |
Molecular Weight: | 107,533 Da |
NCBI Full Name: | Desmoglein-3 |
NCBI Synonym Full Names: | desmoglein 3 |
NCBI Official Symbol: | DSG3 |
NCBI Official Synonym Symbols: | PVA; CDHF6 |
NCBI Protein Information: | desmoglein-3; cadherin family member 6; pemphigus vulgaris antigen; 130-kD pemphigus vulgaris antigen; 130 kDa pemphigus vulgaris antigen |
UniProt Protein Name: | Desmoglein-3 |
UniProt Synonym Protein Names: | 130 kDa pemphigus vulgaris antigen; PVA; Cadherin family member 6 |
Protein Family: | Desmoglein |
UniProt Gene Name: | DSG3 |
UniProt Entry Name: | DSG3_HUMAN |
Antibodies | ELISA Kits |
Anti-Desmoglein-3 Antibody (CAB8412) | Human DSG3 / Desmoglein-3 ELISA Kit |
Anti-Desmoglein 3 Antibody (CAB5227) | Human Desmoglein-3 (DSG3) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |