DNAJB4 Antibody (PACO22052)
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주문- SKU:
- PACO22052
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | DNAJB4 Antibody (PACO22052) |
Antibody SKU: | PACO22052 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from internal of human DNAJB4. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from HepG2 cells, using DNAJB4 antibody. |
Background: | Probable chaperone. |
Synonyms: | DJB4; DnaJ homolog subfamily B member 4; DNAJW; DNJB4; Heat shock 40 kDa protein 1 homolog |
UniProt Protein Function: | DNAJB4: Probable chaperone. Homodimer. The C-terminal section interacts with the C- terminal tail of OPRM1. Interacts also with SDIM1. By heat shock. Expressed in heart, pancreas and skeletal muscle, and to a lesser extent in brain, placenta and liver. |
UniProt Protein Details: | Protein type:Chaperone Chromosomal Location of Human Ortholog: 1p31.1 Cellular Component: cytoplasm; cytosol; nucleoplasm; plasma membrane Molecular Function:chaperone binding; protein binding; unfolded protein binding Biological Process: protein folding; response to heat; response to unfolded protein |
NCBI Summary: | The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] |
UniProt Code: | Q9UDY4 |
NCBI GenInfo Identifier: | 8928155 |
NCBI Gene ID: | 11080 |
NCBI Accession: | Q9UDY4.1 |
UniProt Secondary Accession: | Q9UDY4,Q13431, B2R824, |
UniProt Related Accession: | Q9UDY4 |
Molecular Weight: | 37,807 Da |
NCBI Full Name: | DnaJ homolog subfamily B member 4 |
NCBI Synonym Full Names: | DnaJ heat shock protein family (Hsp40) member B4 |
NCBI Official Symbol: | DNAJB4 |
NCBI Official Synonym Symbols: | DjB4; HLJ1; DNAJW |
NCBI Protein Information: | dnaJ homolog subfamily B member 4 |
UniProt Protein Name: | DnaJ homolog subfamily B member 4 |
UniProt Synonym Protein Names: | Heat shock 40 kDa protein 1 homolog; HSP40 homolog; Heat shock protein 40 homolog; Human liver DnaJ-like protein |
Protein Family: | DnaJ homolog subfamily |
UniProt Gene Name: | DNAJB4 |
UniProt Entry Name: | DNJB4_HUMAN |