DLL4 Antibody (PACO16188)
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주문- SKU:
- PACO16188
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | DLL4 Antibody (PACO16188) |
Antibody SKU: | PACO16188 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human DLL4 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO16188(DLL4 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO16188(DLL4 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. |
Synonyms: | delta-like 4 (Drosophila) |
UniProt Protein Function: | DLL4: Plays a role in the Notch signaling pathway. Activates Notch-1 and Notch-4. Binds to Notch-1 and Notch-4. Expressed in vascular endothelium. |
UniProt Protein Details: | Protein type:Cell development/differentiation; Membrane protein, integral Chromosomal Location of Human Ortholog: 15q15.1 Cellular Component: plasma membrane Molecular Function:protein binding Biological Process: angiogenesis; blood circulation; blood vessel remodeling; negative regulation of cell proliferation; negative regulation of Notch signaling pathway; negative regulation of transcription from RNA polymerase II promoter; Notch receptor processing; Notch signaling pathway; patterning of blood vessels; positive regulation of Notch signaling pathway; signal transduction; T cell differentiation Disease: Adams-oliver Syndrome 6 |
NCBI Summary: | This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NR61 |
NCBI GenInfo Identifier: | 13431490 |
NCBI Gene ID: | 54567 |
NCBI Accession: | Q9NR61.1 |
UniProt Secondary Accession: | Q9NR61,Q3KP23, Q9NQT9, |
UniProt Related Accession: | Q9NR61 |
Molecular Weight: | 75kDa |
NCBI Full Name: | Delta-like protein 4 |
NCBI Synonym Full Names: | delta like canonical Notch ligand 4 |
NCBI Official Symbol: | DLL4 |
NCBI Official Synonym Symbols: | AOS6; hdelta2 |
NCBI Protein Information: | delta-like protein 4 |
UniProt Protein Name: | Delta-like protein 4 |
UniProt Synonym Protein Names: | Drosophila Delta homolog 4; Delta4 |
Protein Family: | Delta-like protein |
UniProt Gene Name: | DLL4 |
Antibodies | ELISA Kits |
Anti-DLL4 Antibody (CAB12943) | Human Delta-like protein 4 (DLL4) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |