DLL1 Antibody (PACO13434)
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주문- SKU:
- PACO13434
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | DLL1 Antibody (PACO13434) |
Antibody SKU: | PACO13434 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | |
Species Reactivity: | Human |
Immunogen: | Human DLL1-Specific |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | delta-like 1 (Drosophila);DLL1;DELTA1;DL1;Delta ; |
UniProt Protein Function: | DLL1: Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. Interacts with Notch receptors. Expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Membrane protein, integral; Cell development/differentiation Chromosomal Location of Human Ortholog: 6q27 Cellular Component: integral to plasma membrane; plasma membrane; extracellular region; cytoplasmic vesicle Molecular Function:protein binding; calcium ion binding; Notch binding Biological Process: regulation of cell adhesion; Notch signaling pathway; negative regulation of myeloid cell differentiation; negative regulation of interleukin-10 production; Notch receptor processing; cell fate determination; compartment specification; somite specification; cell-cell signaling; negative regulation of auditory receptor cell differentiation; hemopoiesis; positive regulation of transcription from RNA polymerase II promoter; heart looping; determination of left/right symmetry; cell differentiation; inner ear development; positive regulation of Notch signaling pathway |
NCBI Summary: | DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. [provided by RefSeq, Jul 2008] |
UniProt Code: | O00548 |
NCBI GenInfo Identifier: | 118582508 |
NCBI Gene ID: | 28514 |
NCBI Accession: | O00548.2 |
UniProt Secondary Accession: | O00548,Q9NU41, Q9UJV2, B2RAK7, B5M0B3, |
UniProt Related Accession: | O00548 |
Molecular Weight: | 723 |
NCBI Full Name: | Delta-like protein 1 |
NCBI Synonym Full Names: | delta-like 1 (Drosophila) |
NCBI Official Symbol: | DLL1 |
NCBI Official Synonym Symbols: | DL1; Delta; DELTA1 |
NCBI Protein Information: | delta-like protein 1; H-Delta-1; drosophila Delta homolog 1 |
UniProt Protein Name: | Delta-like protein 1 |
UniProt Synonym Protein Names: | Drosophila Delta homolog 1; Delta1; H-Delta-1 |
Protein Family: | Delta-like protein |
UniProt Gene Name: | DLL1 |
UniProt Entry Name: | DLL1_HUMAN |