DHTKD1 Antibody (PACO45129)
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주문- SKU:
- PACO45129
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | DHTKD1 Antibody (PACO45129) |
Antibody SKU: | PACO45129 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial protein (1-280AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: DHTKD1 antibody at 1.82µg/ml. Lane 1: Mouse heart tissue. Lane 2: A431 whole cell lysate. Lane 3: MCF-7 whole cell lysate. Lane 4: HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 103 kDa. Observed band size: 103 kDa.. | |
Immunohistochemistry of paraffin-embedded human brain tissue using PACO45129 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human gastric cancer using PACO45129 at dilution of 1:100. |
Background: | The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). |
Synonyms: | Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial (EC 1.2.4.2) (Dehydrogenase E1 and transketolase domain-containing protein 1), DHTKD1, KIAA1630 |
UniProt Protein Function: | DHTKD1: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the alpha-ketoglutarate dehydrogenase family. |
UniProt Protein Details: | Protein type:Oxidoreductase; EC 1.2.4.2 Chromosomal Location of Human Ortholog: 10p14 Cellular Component: cytosol; mitochondrial matrix; mitochondrion; oxoglutarate dehydrogenase complex Molecular Function:oxoglutarate dehydrogenase (succinyl-transferring) activity Biological Process: generation of precursor metabolites and energy; glyoxylate metabolic process; tricarboxylic acid cycle Disease: 2-aminoadipic 2-oxoadipic Aciduria; Charcot-marie-tooth Disease, Axonal, Type 2q |
NCBI Summary: | This gene encodes a component of a mitochondrial 2-oxoglutarate-dehydrogenase-complex-like protein involved in the degradation pathways of several amino acids, including lysine. Mutations in this gene are associated with 2-aminoadipic 2-oxoadipic aciduria and Charcot-Marie-Tooth Disease Type 2Q. [provided by RefSeq, May 2013] |
UniProt Code: | Q96HY7 |
NCBI GenInfo Identifier: | 296434477 |
NCBI Gene ID: | 55526 |
NCBI Accession: | Q96HY7.2 |
UniProt Secondary Accession: | Q96HY7,Q68CU5, Q9BUM8, Q9HCE2, |
UniProt Related Accession: | Q96HY7 |
Molecular Weight: | 103,077 Da |
NCBI Full Name: | Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial |
NCBI Synonym Full Names: | dehydrogenase E1 and transketolase domain containing 1 |
NCBI Official Symbol: | DHTKD1 |
NCBI Official Synonym Symbols: | CMT2Q; AMOXAD |
NCBI Protein Information: | probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial |
UniProt Protein Name: | Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial |
UniProt Synonym Protein Names: | Dehydrogenase E1 and transketolase domain-containing protein 1 |
Protein Family: | Probable 2-oxoglutarate dehydrogenase E1 component |
UniProt Gene Name: | DHTKD1 |
UniProt Entry Name: | DHTK1_HUMAN |
Antibodies |
Anti-DHTKD1 Antibody (CAB8369) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |