DDX20 Antibody (PACO08784)
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주문- SKU:
- PACO08784
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | DDX20 Antibody (PACO08784) |
Antibody SKU: | PACO08784 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human DDX20 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20;DDX20;DKFZp434H052;DP103;GEMIN3 ; |
UniProt Protein Function: | GEMIN3: an ubiquitous DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. Interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. |
UniProt Protein Details: | Protein type:RNA splicing; Nuclear receptor co-regulator; EC 3.6.4.13; Helicase Chromosomal Location of Human Ortholog: 1p21.1-p13.2 Cellular Component: nucleoplasm; cytoskeleton; membrane; transcriptional repressor complex; cytoplasm; SMN complex; nucleus; cytosol Molecular Function:protein domain specific binding; protein binding; DNA binding; ATP-dependent RNA helicase activity; ATP binding Biological Process: oogenesis; assembly of spliceosomal tri-snRNP; RNA processing; spliceosomal snRNP biogenesis; positive regulation of apoptosis; regulation of steroid biosynthetic process; gene expression; negative regulation of transcription from RNA polymerase II promoter |
NCBI Summary: | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UHI6 |
NCBI GenInfo Identifier: | 12643886 |
NCBI Gene ID: | 11218 |
NCBI Accession: | Q9UHI6.2 |
UniProt Secondary Accession: | Q9UHI6,Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659, B4DWV7 |
UniProt Related Accession: | Q9UHI6 |
Molecular Weight: | 824 |
NCBI Full Name: | Probable ATP-dependent RNA helicase DDX20 |
NCBI Synonym Full Names: | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 |
NCBI Official Symbol: | DDX20 |
NCBI Official Synonym Symbols: | DP103; GEMIN3 |
NCBI Protein Information: | probable ATP-dependent RNA helicase DDX20; gemin-3; DEAD box protein 20; component of gems 3; DEAD-box protein DP103; DEAD box protein DP 103; SMN-interacting protein; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20, 103kD |
UniProt Protein Name: | Probable ATP-dependent RNA helicase DDX20 |
UniProt Synonym Protein Names: | Component of gems 3; DEAD box protein 20; DEAD box protein DP 103; Gemin-3 |
Protein Family: | Probable ATP-dependent RNA helicase |
UniProt Gene Name: | DDX20 |
UniProt Entry Name: | DDX20_HUMAN |