DCTN3 Antibody (PACO45070)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO45070
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | DCTN3 Antibody (PACO45070) |
Antibody SKU: | PACO45070 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Dynactin subunit 3 protein (1-176AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO45070 at dilution of 1:100. |
Background: | Together with dynein may be involved in spindle assembly and cytokinesis. |
Synonyms: | Dynactin subunit 3 (Dynactin complex subunit 22 kDa subunit) (p22), DCTN3, DCTN22 |
UniProt Protein Function: | dynactin 3: Together with dynein may be involved in spindle assembly and cytokinesis. Belongs to the dynactin subunit 3 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Microtubule-binding; Motility/polarity/chemotaxis; MotorChromosomal Location of Human Ortholog: 9p13Cellular Component: centrosome; cleavage furrow; cytosol; dynactin complex; midbody; perinuclear region of cytoplasm; spindleMolecular Function: protein binding; structural molecule activityBiological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; cytokinesis; ER to Golgi vesicle-mediated transport; G2/M transition of mitotic cell cycle; microtubule-based process; mitosis |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
UniProt Code: | O75935 |
NCBI GenInfo Identifier: | 6005745 |
NCBI Gene ID: | 11258 |
NCBI Accession: | NP_009165.1 |
UniProt Secondary Accession: | O75935,Q5T1I5, Q5T1I7, Q5T8G3, Q9BPU8, A6NII7, B2RBM5 |
UniProt Related Accession: | O75935 |
Molecular Weight: | |
NCBI Full Name: | dynactin subunit 3 isoform 1 |
NCBI Synonym Full Names: | dynactin subunit 3 |
NCBI Official Symbol: | DCTN3 |
NCBI Official Synonym Symbols: | DCTN22; DCTN-22 |
NCBI Protein Information: | dynactin subunit 3 |
UniProt Protein Name: | Dynactin subunit 3 |
UniProt Synonym Protein Names: | Dynactin complex subunit 22 kDa subunit; p22 |
Protein Family: | Dynactin |
UniProt Gene Name: | DCTN3 |
UniProt Entry Name: | DCTN3_HUMAN |