DAP Antibody (PACO19544)
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주문- SKU:
- PACO19544
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | DAP Antibody (PACO19544) |
Antibody SKU: | PACO19544 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human DAP |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19544(DAP Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19544(DAP Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene encodes a basic, proline-rich, 15-kD protein. The protein acts as a positive mediator of programmed cell death that is induced by interferon-gamma. |
Synonyms: | death-associated protein |
UniProt Protein Function: | DAP: a 15 kDa, proline rich protein that possesses one SH3 binding motif. Negatively regulates autophagy and is involved in mediating interferon-gamma-induced cell death. Localizes in the cytoplasm, but the detailed mechanism of its proapoptotic function is unclear. |
UniProt Protein Details: | Protein type:Autophagy Chromosomal Location of Human Ortholog: 5p15.2 Biological Process: apoptosis; caspase activation; cellular response to amino acid starvation; inhibition of NF-kappaB transcription factor; negative regulation of autophagy; negative regulation of transcription, DNA-dependent |
NCBI Summary: | This gene encodes a basic, proline-rich, 15-kD protein. The protein acts as a positive mediator of programmed cell death that is induced by interferon-gamma. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] |
UniProt Code: | P51397 |
NCBI GenInfo Identifier: | 1706298 |
NCBI Gene ID: | 1611 |
NCBI Accession: | P51397.3 |
UniProt Secondary Accession: | P51397,Q6FGC3, Q9BUC9, |
UniProt Related Accession: | P51397 |
Molecular Weight: | 11,165 Da |
NCBI Full Name: | Death-associated protein 1 |
NCBI Synonym Full Names: | death associated protein |
NCBI Official Symbol: | DAP |
NCBI Protein Information: | death-associated protein 1 |
UniProt Protein Name: | Death-associated protein 1 |
Protein Family: | Dapper |
UniProt Gene Name: | DAP |
UniProt Entry Name: | DAP1_HUMAN |