CXCR5 Antibody (PACO54722)
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주문- SKU:
- PACO54722
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CXCR5 Antibody (PACO54722) |
Antibody SKU: | PACO54722 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human C-X-C chemokine receptor type 5 protein (1-55AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human liver cancer using PACO54722 at dilution of 1:100. | |
Immunofluorescent analysis of HepG2 cells using PACO54722 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). | |
Immunohistochemistry of paraffin-embedded human lymph node tissue using PACO54722 at dilution of 1:100. |
Background: | Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. |
Synonyms: | C-X-C chemokine receptor type 5 (CXC-R5) (CXCR-5) (Burkitt lymphoma receptor 1) (Monocyte-derived receptor 15) (MDR-15) (CD antigen CD185), CXCR5, BLR1 MDR15 |
UniProt Protein Function: | CXCR5: Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 11q23.3 Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane Molecular Function:G-protein coupled receptor activity; protein binding; C-X-C chemokine receptor activity Biological Process: positive regulation of cytokinesis; G-protein coupled receptor protein signaling pathway; B cell activation; immune response; cell motility; chemotaxis; lymph node development |
NCBI Summary: | This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] |
UniProt Code: | P32302 |
NCBI GenInfo Identifier: | 416718 |
NCBI Gene ID: | 643 |
NCBI Accession: | P32302.1 |
UniProt Related Accession: | P32302 |
Molecular Weight: | |
NCBI Full Name: | C-X-C chemokine receptor type 5 |
NCBI Synonym Full Names: | C-X-C motif chemokine receptor 5 |
NCBI Official Symbol: | CXCR5 |
NCBI Official Synonym Symbols: | BLR1; CD185; MDR15 |
NCBI Protein Information: | C-X-C chemokine receptor type 5 |
UniProt Protein Name: | C-X-C chemokine receptor type 5 |
UniProt Synonym Protein Names: | Burkitt lymphoma receptor 1; Monocyte-derived receptor 15; MDR-15; CD_antigen: CD185 |
UniProt Gene Name: | CXCR5 |
UniProt Entry Name: | CXCR5_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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