CTSS Antibody (PACO32900)
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주문- SKU:
- PACO32900
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | CTSS Antibody (PACO32900) |
Antibody SKU: | PACO32900 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Cathepsin S protein (115-331AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO32900 at dilution of 1:100. | |
Western Blot Positive WB detected in: A549 whole cell lysate, 293 whole cell lysate All lanes: CTSS antibody at 1:4000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 38, 32 kDa Observed band size: 38 kDa . |
Background: | Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L. |
Synonyms: | Cathepsin S (EC 3.4.22.27), CTSS |
UniProt Protein Function: | CTSS: Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond- specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. Belongs to the peptidase C1 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Protease; EC 3.4.22.27 Chromosomal Location of Human Ortholog: 1q21 Cellular Component: extracellular region; extracellular space; intracellular membrane-bound organelle; lysosomal lumen; lysosome Molecular Function:collagen binding; cysteine-type endopeptidase activity; fibronectin binding; laminin binding; proteoglycan binding; serine-type endopeptidase activity Biological Process: adaptive immune response; antigen processing and presentation; antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen; collagen catabolic process; extracellular matrix disassembly; immune response; protein processing; proteolysis; proteolysis involved in cellular protein catabolic process; response to acidity; toll-like receptor signaling pathway |
NCBI Summary: | The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010] |
UniProt Code: | P25774 |
NCBI GenInfo Identifier: | 88984046 |
NCBI Gene ID: | 1520 |
NCBI Accession: | P25774.3 |
UniProt Secondary Accession: | P25774,Q5T5I0, Q6FHS5, Q9BUG3, B4DWC9, D3DV05, |
UniProt Related Accession: | P25774 |
Molecular Weight: | 31,626 Da |
NCBI Full Name: | Cathepsin S |
NCBI Synonym Full Names: | cathepsin S |
NCBI Official Symbol: | CTSS |
NCBI Protein Information: | cathepsin S |
UniProt Protein Name: | Cathepsin S |
Protein Family: | Cathepsin |
UniProt Gene Name: | CTSS |
UniProt Entry Name: | CATS_HUMAN |
Antibodies | ELISA Kits |
Anti-CTSS Antibody (CAB13482) | Human Cathepsin S / CTSS ELISA Kit |
Anti-CTSS Antibody (CAB1874) | Human Cathepsin S (CTSS) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |