CTNNBL1 Antibody (PACO16087)
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주문- SKU:
- PACO16087
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CTNNBL1 Antibody (PACO16087) |
Antibody SKU: | PACO16087 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:100-1:300 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human CTNNBL1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16087(CTNNBL1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO16087(CTNNBL1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. |
Synonyms: | catenin, β like 1 |
UniProt Protein Function: | CTNNBL1: Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:RNA splicing; Spliceosome Chromosomal Location of Human Ortholog: 20q11.23-q12 Cellular Component: nucleoplasm; spliceosome; membrane; cytoplasm; nucleus Molecular Function:protein binding; enzyme binding Biological Process: nuclear mRNA splicing, via spliceosome; somatic diversification of immunoglobulins; positive regulation of apoptosis; apoptosis; RNA splicing; gene expression |
NCBI Summary: | The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Jul 2013] |
UniProt Code: | Q8WYA6 |
NCBI GenInfo Identifier: | 29840792 |
NCBI Gene ID: | 56259 |
NCBI Accession: | Q8WYA6.1 |
UniProt Related Accession: | Q8WYA6 |
Molecular Weight: | 65.2kDa |
NCBI Full Name: | Beta-catenin-like protein 1 |
NCBI Synonym Full Names: | catenin beta like 1 |
NCBI Official Symbol: | CTNNBL1 |
NCBI Official Synonym Symbols: | NAP; P14L; PP8304; C20orf33; dJ633O20.1 |
NCBI Protein Information: | beta-catenin-like protein 1 |
UniProt Protein Name: | Beta-catenin-like protein 1 |
UniProt Synonym Protein Names: | Nuclear-associated protein; NAP; Testis development protein NYD-SP19 |
Protein Family: | Beta-catenin-like protein |
UniProt Gene Name: | CTNNBL1 |
UniProt Entry Name: | CTBL1_HUMAN |
Antibodies | ELISA Kits |
Anti-CTNNBL1 Antibody (CAB6572) | Human Neutrophil Alkaline Phosphatase / NAP ELISA Kit |
CTNNBL1 Antibody (PACO08661) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |