CTNNBIP1 Antibody (PACO16085)
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주문- SKU:
- PACO16085
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | CTNNBIP1 Antibody (PACO16085) |
Antibody SKU: | PACO16085 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human CTNNBIP1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO16085(CTNNBIP1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO16085(CTNNBIP1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. |
Synonyms: | catenin, β interacting protein 1 |
UniProt Protein Function: | CTNNBIP1: Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway. Belongs to the CTNNBIP1 family. |
UniProt Protein Details: | Protein type:Cell development/differentiation; Inhibitor Chromosomal Location of Human Ortholog: 1p36.22 Cellular Component: nucleoplasm; cytoplasm; nucleus; beta-catenin destruction complex; cytosol Molecular Function:protein binding; beta-catenin binding Biological Process: anterior/posterior pattern formation; positive regulation of monocyte differentiation; positive regulation of osteoblast differentiation; Wnt receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; ureteric bud branching; negative regulation of smooth muscle cell proliferation; negative regulation of transcription factor activity; negative regulation of protein binding; regulation of vascular permeability during acute inflammatory response; negative regulation of DNA binding |
NCBI Summary: | The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NSA3 |
NCBI GenInfo Identifier: | 59889555 |
NCBI Gene ID: | 56998 |
NCBI Accession: | NP_001012329.1 |
UniProt Secondary Accession: | Q9NSA3,Q9JJN6, |
UniProt Related Accession: | Q9NSA3 |
Molecular Weight: | 9,170 Da |
NCBI Full Name: | beta-catenin-interacting protein 1 |
NCBI Synonym Full Names: | catenin, beta interacting protein 1 |
NCBI Official Symbol: | CTNNBIP1 |
NCBI Official Synonym Symbols: | ICAT |
NCBI Protein Information: | beta-catenin-interacting protein 1; beta-catenin-interacting protein ICAT; inhibitor of beta-catenin and Tcf-4 |
UniProt Protein Name: | Beta-catenin-interacting protein 1 |
UniProt Synonym Protein Names: | Inhibitor of beta-catenin and Tcf-4 |
UniProt Gene Name: | CTNNBIP1 |
UniProt Entry Name: | CNBP1_HUMAN |
Antibodies |
Anti-CTNNBIP1 Antibody (CAB7122) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |