CTGF Antibody (PACO17736)
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주문- SKU:
- PACO17736
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CTGF Antibody (PACO17736) |
Antibody SKU: | PACO17736 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:25-1:50 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human CTGF |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Hela cells, Primary antibody: PACO17736(CTGF Antibody) at dilution 1/850, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO17736(CTGF Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. |
Synonyms: | Connective tissue growth factor |
UniProt Protein Function: | CTGF: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Belongs to the CCN family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cell adhesion; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 6q23.2 Cellular Component: extracellular region; Golgi apparatus; intracellular membrane-bound organelle; plasma membrane Molecular Function:protein binding; protein C-terminus binding Biological Process: epidermis development; positive regulation of cell differentiation; positive regulation of JNK cascade; positive regulation of stress fiber formation; response to wounding; transcription initiation from RNA polymerase II promoter |
NCBI Summary: | The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009] |
UniProt Code: | P29279 |
NCBI GenInfo Identifier: | 116241320 |
NCBI Gene ID: | 1490 |
NCBI Accession: | P29279.2 |
UniProt Secondary Accession: | P29279,Q6LCY0, Q96A79, Q96QX2, Q9UDL6, E1P578, |
UniProt Related Accession: | P29279 |
Molecular Weight: | 38kDa |
NCBI Full Name: | Connective tissue growth factor |
NCBI Synonym Full Names: | connective tissue growth factor |
NCBI Official Symbol: | CTGF |
NCBI Official Synonym Symbols: | CCN2; NOV2; HCS24; IGFBP8 |
NCBI Protein Information: | connective tissue growth factor |
UniProt Protein Name: | Connective tissue growth factor |
UniProt Synonym Protein Names: | CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP-8 |
Protein Family: | Connective tissue growth factor |
UniProt Gene Name: | CTGF |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |