CSTF2 Antibody (PACO43790)
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주문- SKU:
- PACO43790
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CSTF2 Antibody (PACO43790) |
Antibody SKU: | PACO43790 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Cleavage stimulation factor subunit 2 protein (1-180AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot All lanes: CSTF2 antibody at 6µg/ml Lane 1: Hela whole cell lysate Lane 2: Jurkat whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 61, 60 kDa Observed band size: 61 kDa | |
Immunohistochemistry of paraffin-embedded human liver cancer using PACO43790 at dilution of 1:100 |
Background: | One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs (By similarity). |
Synonyms: | Cleavage stimulation factor subunit 2 (CF-1 64 kDa subunit) (Cleavage stimulation factor 64 kDa subunit) (CSTF 64 kDa subunit) (CstF-64), CSTF2 |
UniProt Protein Function: | CSTF2: One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:RNA splicing; RNA-binding Chromosomal Location of Human Ortholog: Xq22.1 Cellular Component: mRNA cleavage and polyadenylation specificity factor complex; nucleoplasm; nucleus Molecular Function:mRNA binding; protein binding; RNA binding Biological Process: mRNA 3'-end processing; mRNA cleavage; nuclear mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; tRNA splicing |
NCBI Summary: | This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs. [provided by RefSeq, Jul 2008] |
UniProt Code: | P33240 |
NCBI GenInfo Identifier: | 461847 |
NCBI Gene ID: | 1478 |
NCBI Accession: | P33240.1 |
UniProt Secondary Accession: | P33240,Q5H951, Q6LA74, Q8N502, |
UniProt Related Accession: | P33240 |
Molecular Weight: | 59,251 Da |
NCBI Full Name: | Cleavage stimulation factor subunit 2 |
NCBI Synonym Full Names: | cleavage stimulation factor subunit 2 |
NCBI Official Symbol: | CSTF2 |
NCBI Official Synonym Symbols: | CstF-64 |
NCBI Protein Information: | cleavage stimulation factor subunit 2 |
UniProt Protein Name: | Cleavage stimulation factor subunit 2 |
UniProt Synonym Protein Names: | CF-1 64 kDa subunit; Cleavage stimulation factor 64 kDa subunit; CSTF 64 kDa subunit; CstF-64 |
Protein Family: | Cleavage stimulation factor |
UniProt Gene Name: | CSTF2 |
UniProt Entry Name: | CSTF2_HUMAN |