CSRP2 Antibody (PACO45500)
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주문- SKU:
- PACO45500
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CSRP2 Antibody (PACO45500) |
Antibody SKU: | PACO45500 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Cysteine and glycine-rich protein 2 protein (1-193AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: CSRP2 antibody at 5.74µg/ml. Lane 1: Mouse lung tissue. Lane 2: A375 whole cell lysate. Lane 3: A549 whole cell lysate. Lane 4: HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 21 kDa. Observed band size: 21 kDa.. | |
Immunohistochemistry of paraffin-embedded human liver cancer using PACO45500 at dilution of 1:100. |
Background: | Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system. |
Synonyms: | Cysteine and glycine-rich protein 2 (Cysteine-rich protein 2) (CRP2) (LIM domain only protein 5) (LMO-5) (Smooth muscle cell LIM protein) (SmLIM), CSRP2, LMO5 SMLIM |
UniProt Protein Function: | CSRP2: a LIM protein that is differentially regulated and preferentially expressed in aortic smooth muscle cells. Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system. |
UniProt Protein Details: | Protein type:Cell development/differentiation Chromosomal Location of Human Ortholog: 12q21.1 Cellular Component: focal adhesion; nucleus Molecular Function:zinc ion binding Biological Process: multicellular organismal development; cell differentiation |
NCBI Summary: | CSRP2 is a member of the CSRP family of genes, encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3. [provided by RefSeq] |
UniProt Code: | Q16527 |
NCBI GenInfo Identifier: | 4503101 |
NCBI Gene ID: | 1466 |
NCBI Accession: | NP_001312.1 |
UniProt Secondary Accession: | Q16527,Q93030, |
UniProt Related Accession: | Q16527 |
Molecular Weight: | 20,954 Da |
NCBI Full Name: | cysteine and glycine-rich protein 2 |
NCBI Synonym Full Names: | cysteine and glycine-rich protein 2 |
NCBI Official Symbol: | CSRP2 |
NCBI Official Synonym Symbols: | CRP2; LMO5; SmLIM |
NCBI Protein Information: | cysteine and glycine-rich protein 2; LMO-5; cysteine-rich protein 2; LIM domain only protein 5; smooth muscle cell LIM protein; LIM domain only 5, smooth muscle |
UniProt Protein Name: | Cysteine and glycine-rich protein 2 |
UniProt Synonym Protein Names: | Cysteine-rich protein 2; CRP2; LIM domain only protein 5; LMO-5; Smooth muscle cell LIM protein |
Protein Family: | Cysteine and glycine-rich protein |
UniProt Gene Name: | CSRP2 |
UniProt Entry Name: | CSRP2_HUMAN |