CSNK1G3 Antibody (PACO63919)
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주문- SKU:
- PACO63919
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CSNK1G3 Antibody (PACO63919) |
Antibody SKU: | PACO63919 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Casein kinase I isoform gamma-3 protein (1-204AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunofluorescence staining of A549 cells with PACO63919 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acid, c proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity). |
Synonyms: | Casein kinase I isoform gamma-3 (CKI-γ 3) (EC 2.7.11.1), CSNK1G3 |
UniProt Protein Function: | CK1G3: Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate. Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Protein kinase, CK1; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; CK1 group; CK1 family Chromosomal Location of Human Ortholog: 5q23 Cellular Component: cytoplasm; nucleus Molecular Function:protein kinase activity; protein serine/threonine kinase activity Biological Process: endocytosis; peptidyl-serine phosphorylation; protein modification process; regulation of cell shape; signal transduction; Wnt receptor signaling pathway |
NCBI Summary: | This gene encodes a member of a family of serine/threonine protein kinases that phosphorylate caseins and other acidic proteins. A related protein in the African clawed frog participates in the transmission of Wnt/beta-catenin signaling. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] |
UniProt Code: | Q9Y6M4 |
NCBI GenInfo Identifier: | 47117932 |
NCBI Gene ID: | 1456 |
NCBI Accession: | Q9Y6M4.2 |
UniProt Secondary Accession: | Q9Y6M4,Q86WZ7, Q9Y6M3, A8K040, B4DSH2, B7Z9Q4, E7EVD0 |
UniProt Related Accession: | Q9Y6M4 |
Molecular Weight: | 36,492 Da |
NCBI Full Name: | Casein kinase I isoform gamma-3 |
NCBI Synonym Full Names: | casein kinase 1 gamma 3 |
NCBI Official Symbol: | CSNK1G3 |
NCBI Official Synonym Symbols: | CSNK1G3L; CKI-gamma 3 |
NCBI Protein Information: | casein kinase I isoform gamma-3 |
UniProt Protein Name: | Casein kinase I isoform gamma-3 |
Protein Family: | Casein kinase |
UniProt Gene Name: | CSNK1G3 |
UniProt Entry Name: | KC1G3_HUMAN |
Antibodies |
Anti-CSNK1G3 Antibody (CAB13013) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |