CORO1B Antibody (PACO47126)
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주문- SKU:
- PACO47126
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CORO1B Antibody (PACO47126) |
Antibody SKU: | PACO47126 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Coronin-1B protein (252-453AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO47126 at dilution of 1:100. | |
Immunofluorescent analysis of HepG2 cells using PACO47126 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). | |
Immunohistochemistry of paraffin-embedded human gastric cancer using PACO47126 at dilution of 1:100. |
Background: | Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction (By similarity). |
Synonyms: | Coronin-1B (Coronin-2), CORO1B |
UniProt Protein Function: | coronin 1B: an actin-binding protein that regulates leading edge dynamics and cell motility in fibroblasts. Coordinates the Arp2/3 complex (includes ACTR2, ARPC1B and ARPC2) cofilin activities at the leading edge. Localized to the leading edge in fibroblasts and weakly along actin stress fibers. Phosphorylation by PKC regulates the interaction with the Arp2/3 complex and cell motility in fibroblasts. Belongs to the WD repeat coronin family. |
UniProt Protein Details: | Protein type:Actin-binding; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 11q13.2 Cellular Component: actin filament; cytoplasm; cytosol; focal adhesion; lamellipodium; leading edge; perinuclear region of cytoplasm; plasma membrane; stress fiber Molecular Function:actin filament binding; identical protein binding; protein binding Biological Process: actin cytoskeleton organization and biogenesis; actin filament bundle formation; cell migration; ruffle organization and biogenesis; wound healing |
NCBI Summary: | Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell motility (Cai et al., 2005 [PubMed 16027158]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q9BR76 |
NCBI GenInfo Identifier: | 21263481 |
NCBI Gene ID: | 57175 |
NCBI Accession: | Q9BR76.1 |
UniProt Secondary Accession: | Q9BR76,B2RD45, |
UniProt Related Accession: | Q9BR76 |
Molecular Weight: | 54,235 Da |
NCBI Full Name: | Coronin-1B |
NCBI Synonym Full Names: | coronin 1B |
NCBI Official Symbol: | CORO1B |
NCBI Official Synonym Symbols: | CORONIN-2 |
NCBI Protein Information: | coronin-1B |
UniProt Protein Name: | Coronin-1B |
UniProt Synonym Protein Names: | Coronin-2 |
Protein Family: | Coronin |
UniProt Gene Name: | CORO1B |
UniProt Entry Name: | COR1B_HUMAN |
Antibodies |
Anti-CORO1B Antibody (CAB14593) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |