COL2A1 Antibody (PACO14271)
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주문- SKU:
- PACO14271
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | COL2A1 Antibody (PACO14271) |
Antibody SKU: | PACO14271 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:15-1:50 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human COL2A1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO14271(COL2A1 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane: 293T cells, Primary antibody: PACO14271(COL2A1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO14271(COL2A1 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. |
Synonyms: | collagen, type II, α 1 |
UniProt Protein Function: | Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. |
NCBI Summary: | This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | P02458 |
NCBI GenInfo Identifier: | 124056489 |
NCBI Gene ID: | 1280 |
NCBI Accession: | P02458.3 |
UniProt Secondary Accession: | P02458,Q12985, Q14009, Q14044, Q14045, Q14046, Q14047 Q14056, Q14058, Q16672, Q1JQ82, A6NGA0, |
UniProt Related Accession: | P02458 |
Molecular Weight: | 134,389 Da |
NCBI Full Name: | Collagen alpha-1(II) chain |
NCBI Synonym Full Names: | collagen type II alpha 1 chain |
NCBI Official Symbol: | COL2A1 |
NCBI Official Synonym Symbols: | AOM; ANFH; SEDC; STL1; COL11A3 |
NCBI Protein Information: | collagen alpha-1(II) chain |
UniProt Protein Name: | Collagen alpha-1(II) chain |
UniProt Synonym Protein Names: | Alpha-1 type II collagenCurated |
UniProt Gene Name: | COL2A1 |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |