CNNM3 Antibody (PACO14314)
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주문- SKU:
- PACO14314
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CNNM3 Antibody (PACO14314) |
Antibody SKU: | PACO14314 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human CNNM3 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse liver tissue, Primary antibody: PACO14314(CNNM3 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO14314(CNNM3 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | The ACDP3 gene, designated CNNM3 by the HUGO Nomenclature Committee, encodes a deduced 707-amino acid, protein. Northern blot analysis revealed ubiquitous expression of CNNM3. Immunofluorescence studies showed that all 4 CNMM proteins are predominantly localized in the nucleus. Acdp3 contains 4 transmembrane domains, 2 CBS domains, a DUF21 domain, and a cNMP-binding domain. It also has large alanine- and leucine-rich regions. Northern blot analysis detected variable Acdp3 expression in all mouse tissues examined, with highest expression in brain, kidney, liver, and heart. |
Synonyms: | cyclin and CBS domain divalent metal cation transport mediator 3 |
UniProt Protein Function: | CNNM3: Probable metal transporter. Belongs to the ACDP family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Cell cycle regulation Chromosomal Location of Human Ortholog: 2p12-p11.2 Cellular Component: membrane; integral to membrane; plasma membrane Molecular Function:protein binding Biological Process: ion transport |
UniProt Code: | Q8NE01 |
NCBI GenInfo Identifier: | 74751242 |
NCBI Gene ID: | 26505 |
NCBI Accession: | Q8NE01.1 |
UniProt Secondary Accession: | Q8NE01,Q8TBV4, Q96IW4, Q9NRK4, Q9NXW6, B3KX67, |
UniProt Related Accession: | Q8NE01 |
Molecular Weight: | 707 |
NCBI Full Name: | Metal transporter CNNM3 |
NCBI Synonym Full Names: | cyclin and CBS domain divalent metal cation transport mediator 3 |
NCBI Official Symbol: | CNNM3 |
NCBI Official Synonym Symbols: | ACDP3 |
NCBI Protein Information: | metal transporter CNNM3; cyclin M3; cyclin-M3; ancient conserved domain protein 3; ancient conserved domain-containing protein 3 |
UniProt Protein Name: | Metal transporter CNNM3 |
UniProt Synonym Protein Names: | Ancient conserved domain-containing protein 3; Cyclin-M3 |
Protein Family: | Metal transporter |
UniProt Gene Name: | CNNM3 |
UniProt Entry Name: | CNNM3_HUMAN |