UniProt Protein Function: | CLEC2D: Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon- gamma. Binds high molecular weight sulfated glycosaminoglycans. 6 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 12p13 Cellular Component: cell surface; membrane; endoplasmic reticulum; integral to plasma membrane Molecular Function:transmembrane receptor activity; carbohydrate binding Biological Process: cell surface receptor linked signal transduction |
NCBI Summary: | This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Oct 2010] |
UniProt Code: | Q9UHP7 |
NCBI GenInfo Identifier: | 74753331 |
NCBI Gene ID: | 29121 |
NCBI Accession: | Q9UHP7.1 |
UniProt Secondary Accession: | Q9UHP7,Q6YID5, Q8WUP7, Q9HD37, Q9HD38, D6CI39, D6CI40 D6CI41, |
UniProt Related Accession: | Q9UHP7 |
Molecular Weight: | 10,823 Da |
NCBI Full Name: | C-type lectin domain family 2 member D |
NCBI Synonym Full Names: | C-type lectin domain family 2, member D |
NCBI Official Symbol: | CLEC2D |
NCBI Official Synonym Symbols: | CLAX; LLT1; OCIL |
NCBI Protein Information: | C-type lectin domain family 2 member D; LLT-1; C-type lectin related f; lectin-like transcript 1; lectin-like NK cell receptor; osteoclast inhibitory lectin; C-type lectin superfamily 2, member D |
UniProt Protein Name: | C-type lectin domain family 2 member D |
UniProt Synonym Protein Names: | Lectin-like NK cell receptor; Lectin-like transcript 1; LLT-1; Osteoclast inhibitory lectin |
Protein Family: | C-type lectin domain family |
UniProt Gene Name: | CLEC2D |
UniProt Entry Name: | CLC2D_HUMAN |