CLEC16A Antibody (PACO20101)
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주문- SKU:
- PACO20101
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CLEC16A Antibody (PACO20101) |
Antibody SKU: | PACO20101 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human CLEC16A |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20101(CLEC16A Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene encodes a member of the C-type lectin domain containing family. Single nucleotide polymorphisms in introns of this gene have been associated with diabetes mellitus, multiple sclerosis and rheumatoid arthritis. Multiple transcript variants encoding different isoforms have been found for this gene. |
Synonyms: | C-type lectin domain family 16, member A |
UniProt Protein Function: | CLEC16A: Insulin-dependent diabetes mellitus is significantly associated with variation within a 233-kb linkage disequilibrium block on chromosome 16p13 that includes KIAA0350. Three common non-coding variants of KIAA0350 in strong linkage disequilibrium reach genome-wide significance for association with the disease (PubMed:17632545). Belongs to the CLEC16A/gop-1 family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 16p13.13 Cellular Component: lysosomal membrane; endosome membrane Biological Process: autophagy |
NCBI Summary: | This gene encodes a member of the C-type lectin domain containing family. Single nucleotide polymorphisms in introns of this gene have been associated with diabetes mellitus, multiple sclerosis and rheumatoid arthritis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] |
UniProt Code: | Q2KHT3 |
NCBI GenInfo Identifier: | 54792782 |
NCBI Gene ID: | 23274 |
NCBI Accession: | NP_056041.1 |
UniProt Secondary Accession: | Q2KHT3,O15058, Q6ZTB2, |
UniProt Related Accession: | Q2KHT3 |
Molecular Weight: | 14,283 Da |
NCBI Full Name: | protein CLEC16A isoform 1 |
NCBI Synonym Full Names: | C-type lectin domain family 16 member A |
NCBI Official Symbol: | CLEC16A |
NCBI Official Synonym Symbols: | Gop-1; KIAA0350 |
NCBI Protein Information: | protein CLEC16A |
UniProt Protein Name: | Protein CLEC16A |
Protein Family: | Protein |
UniProt Gene Name: | CLEC16A |
UniProt Entry Name: | CL16A_HUMAN |